Prevalence of COVID-19 Among Children and Adolescents While Easing Lockdown Restrictions in Cologne, North Rhine-Westphalia, Germany.
Identifieur interne : 000217 ( Main/Exploration ); précédent : 000216; suivant : 000218Prevalence of COVID-19 Among Children and Adolescents While Easing Lockdown Restrictions in Cologne, North Rhine-Westphalia, Germany.
Auteurs : Robert Walter Körner [Allemagne] ; Lutz Thorsten Weber [Allemagne]Source :
- Klinische Padiatrie [ 1439-3824 ] ; 2021.
Abstract
BACKGROUND
In Germany, widespread full closures of schools and day care facilities were part of lockdown measures to control the spread of coronavirus disease 2019 (COVID-19). In the state of North Rhine-Westphalia closures took place on March 16, 2020 and were gradually eased from end of April 2020 until beginning of June 2020.
OBJECTIVE
This study aims to evaluate the prevalence of COVID-19 among children and adolescents during the reopening period of schools and day care facilities in Cologne, North Rhine-Westphalia, Germany. It further depicts medical history and results of physical examinations of pediatric patients undergoing a test for severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2).
METHODS
Testing for SARS-CoV-2 was carried out by a naso- and / or oropharyngeal swab by local pediatricians at the time of presentation. Samples were analyzed by real-time reverse transcription polymerase chain reaction (RT-PCR). Medical history and physical examination results were retrospectively analyzed.
RESULTS
525 children and adolescents presented mainly with mild upper respiratory tract infections. Three patients were diagnosed with COVID-19. Their medical history and examination results did not stand out from the other patients.
CONCLUSION
A precautious stepwise opening of schools and day care facilities was not associated with the occurrence of a relevant prevalence of COVID-19 among children and adolescents. However, a low general prevalence of COVID-19 at the end of the observation period has to be taken into account. Systematic testing might enable adjusted regulations in favor of full closures, especially in the light of increasing evidence for pediatric patients constituting a low-risk group for COVID-19.
DOI: 10.1055/a-1341-9530
PubMed: 33461226
Affiliations:
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Robert Walter" uniqKey="Korner R" first="Robert Walter" last="Körner">Robert Walter Körner</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University Hospital Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatrics, University Hospital Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, University of Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Faculty of Medicine, University of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Weber, Lutz Thorsten" sort="Weber, Lutz Thorsten" uniqKey="Weber L" first="Lutz Thorsten" last="Weber">Lutz Thorsten Weber</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University Hospital Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatrics, University Hospital Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, University of Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Faculty of Medicine, University of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author></analytic><series><title level="j">Klinische Padiatrie</title><idno type="eISSN">1439-3824</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>In Germany, widespread full closures of schools and day care facilities were part of lockdown measures to control the spread of coronavirus disease 2019 (COVID-19). In the state of North Rhine-Westphalia closures took place on March 16, 2020 and were gradually eased from end of April 2020 until beginning of June 2020.</p></div><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>This study aims to evaluate the prevalence of COVID-19 among children and adolescents during the reopening period of schools and day care facilities in Cologne, North Rhine-Westphalia, Germany. It further depicts medical history and results of physical examinations of pediatric patients undergoing a test for severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2).</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>Testing for SARS-CoV-2 was carried out by a naso- and / or oropharyngeal swab by local pediatricians at the time of presentation. Samples were analyzed by real-time reverse transcription polymerase chain reaction (RT-PCR). Medical history and physical examination results were retrospectively analyzed.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>525 children and adolescents presented mainly with mild upper respiratory tract infections. Three patients were diagnosed with COVID-19. Their medical history and examination results did not stand out from the other patients.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>A precautious stepwise opening of schools and day care facilities was not associated with the occurrence of a relevant prevalence of COVID-19 among children and adolescents. However, a low general prevalence of COVID-19 at the end of the observation period has to be taken into account. Systematic testing might enable adjusted regulations in favor of full closures, especially in the light of increasing evidence for pediatric patients constituting a low-risk group for COVID-19.</p></div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33461226</PMID><DateRevised><Year>2021</Year><Month>01</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1439-3824</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2021</Year><Month>Jan</Month><Day>18</Day></PubDate></JournalIssue><Title>Klinische Padiatrie</Title><ISOAbbreviation>Klin Padiatr</ISOAbbreviation></Journal><ArticleTitle>Prevalence of COVID-19 Among Children and Adolescents While Easing Lockdown Restrictions in Cologne, North Rhine-Westphalia, Germany.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1055/a-1341-9530</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In Germany, widespread full closures of schools and day care facilities were part of lockdown measures to control the spread of coronavirus disease 2019 (COVID-19). In the state of North Rhine-Westphalia closures took place on March 16, 2020 and were gradually eased from end of April 2020 until beginning of June 2020.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">This study aims to evaluate the prevalence of COVID-19 among children and adolescents during the reopening period of schools and day care facilities in Cologne, North Rhine-Westphalia, Germany. It further depicts medical history and results of physical examinations of pediatric patients undergoing a test for severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Testing for SARS-CoV-2 was carried out by a naso- and / or oropharyngeal swab by local pediatricians at the time of presentation. Samples were analyzed by real-time reverse transcription polymerase chain reaction (RT-PCR). Medical history and physical examination results were retrospectively analyzed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">525 children and adolescents presented mainly with mild upper respiratory tract infections. Three patients were diagnosed with COVID-19. Their medical history and examination results did not stand out from the other patients.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">A precautious stepwise opening of schools and day care facilities was not associated with the occurrence of a relevant prevalence of COVID-19 among children and adolescents. However, a low general prevalence of COVID-19 at the end of the observation period has to be taken into account. Systematic testing might enable adjusted regulations in favor of full closures, especially in the light of increasing evidence for pediatric patients constituting a low-risk group for COVID-19.</AbstractText><CopyrightInformation>Thieme. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y" EqualContrib="N"><LastName>Körner</LastName><ForeName>Robert Walter</ForeName><Initials>RW</Initials><Identifier Source="ORCID">0000-0003-3164-4952</Identifier><AffiliationInfo><Affiliation>Department of Pediatrics, University Hospital Cologne, Cologne, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Medicine, University of Cologne, Cologne, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y" EqualContrib="N"><LastName>Weber</LastName><ForeName>Lutz Thorsten</ForeName><Initials>LT</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, University Hospital Cologne, Cologne, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Medicine, University of Cologne, Cologne, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Prävalenz von COVID-19 bei Kindern und Jungendlichen während der Lockerung von Lockdown-Maßnahmen in Köln, Nordrhein-Westfalen, Deutschland.</VernacularTitle><ArticleDate DateType="Electronic"><Year>2021</Year><Month>01</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Klin Padiatr</MedlineTA><NlmUniqueID>0326144</NlmUniqueID><ISSNLinking>0300-8630</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><OtherAbstract Type="Publisher" Language="ger"><AbstractText Label="HINTERGRUND" NlmCategory="UNASSIGNED">In Deutschland zählt die Schließung von Schulen und Kindertagesstätten zu den Maßnahmen, welche die Ausbreitung von Coronavirus disease 2019 (COVID-19) begrenzen sollen. In Nordrhein-Westfalen fanden die ersten Schließungen am 16. März 2020 statt und wurden von Ende April bis Anfang Juni 2020 schrittweise gelockert. ZIEL: Diese Studie soll einen Einblick in die Prävalenz von COVID-19 bei Kindern und Jugendlichen während der Wiedereröffnungsphase der Schulen und Kindertagesstätten in Köln, Nordrhein-Westfalen, geben. Weiterhin sollen die Anamnese und die Ergebnisse klinischer Untersuchungen der Patienten erfasst werden, bei denen ein Test auf das severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) vorgenommen wird.</AbstractText><AbstractText Label="METHODEN" NlmCategory="UNASSIGNED">Die Testung auf SARS-CoV-2 wurde durch einen naso- und / oder oropharyngealen Abstrich durch niedergelassene Kinderärzte vorgenommen. Die Proben wurden mittels real-time reverse transcription polymerase chain reaction (RT-PCR) analysiert. Die Anamnese und die Ergebnisse der körperlichen Untersuchungen wurden retrospektiv ausgewertet. Ergebnis Es wurden 525 Kinder und Jugendliche mit vorwiegend milden Infektionen der oberen Atemwege eingeschlossen. Bei drei Patienten wurde COVID-19 diagnostiziert. Ihre Anamnese und die Ergebnisse der körperlichen Untersuchung unterschied sich nicht merklich von den anderen Patienten.</AbstractText><AbstractText Label="SCHLUSSFOLGERUNG" NlmCategory="UNASSIGNED"> Eine vorsichtige und schrittweise Wiedereröffnung der Schulen und Kindertagesstätten war nicht mit einer relevanten Prävalenz von COVID-19 bei Kindern- und Jugendlichen vergesellschaftet. Allerdings muss berücksichtigt werden, dass zum Zeitpunkt der Untersuchung eine niedrige Gesamtprävelanz in der Bevölkerung vorlag. Eine systematische Testung in Schulen und Kindertagesstätten und spezifische Regulationsmaßnahmen erscheinen gegenüber Vollschließungen vorteilhaft. Dies insbesondere in Anbetracht des niedrigen Risikos für Kinder- und Jugendliche, an COVID-19 schwer zu erkranken.</AbstractText></OtherAbstract><CoiStatement>The authors declare that they have no conflict of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>1</Month><Day>18</Day><Hour>20</Hour><Minute>17</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2021</Year><Month>1</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>1</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33461226</ArticleId><ArticleId IdType="doi">10.1055/a-1341-9530</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Korner, Robert Walter" sort="Korner, Robert Walter" uniqKey="Korner R" first="Robert Walter" last="Körner">Robert Walter Körner</name></noRegion><name sortKey="Korner, Robert Walter" sort="Korner, Robert Walter" uniqKey="Korner R" first="Robert Walter" last="Körner">Robert Walter Körner</name><name sortKey="Weber, Lutz Thorsten" sort="Weber, Lutz Thorsten" uniqKey="Weber L" first="Lutz Thorsten" last="Weber">Lutz Thorsten Weber</name><name sortKey="Weber, Lutz Thorsten" sort="Weber, Lutz Thorsten" uniqKey="Weber L" first="Lutz Thorsten" last="Weber">Lutz Thorsten Weber</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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